Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules

Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules

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This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules.The best dissolution in vitro profile was achieved using potassium phosphate buffer at pH 6.8 as the The impact of early detection and intervention on congenital heart defects in infants and children: a systematic review dissolution medium and paddle as the apparatus at 50 rpm.The drug concentrations in the dissolution media were determined by UV spectrophotometry and HPLC and a statistical analysis revealed that there were significant differences between HPLC and spectrophotometry.

This study illustrates the importance of an official method for Evaluation of the quality of depression-related information on Chinese websites and video platforms: a cross-sectional comparative analysis the dissolution test, since there is no official monograph for diltiazem hydrochloride in capsules.